Thermal behavior and decomposition kinetics of rifampicin polymorphs under isothermal and non-isothermal conditions

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Thermal behavior and decomposition kinetics of rifampicin polymorphs under isothermal and non-isothermal conditions

The thermal behavior of two polymorphic forms of rifampicin was studied by DSC and TG/DTG. The thermoanalytical results clearly showed the differences between the two crystalline forms. Polymorph I was the most thermally stable form, the DSC curve showed no fusion for this species and the thermal decomposition process occurred around 245 °C. The DSC curve of polymorph II showed two consecutive ...

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ژورنال

عنوان ژورنال: Brazilian Journal of Pharmaceutical Sciences

سال: 2010

ISSN: 1984-8250

DOI: 10.1590/s1984-82502010000200022